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Cell bio 2 wks ago
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Multiadhesive Glycoproteins
Proteins in the ECM that promote cell adhesion.
Ground Substance
A component of the ECM containing primarily glycosaminoglycans (GAGs), proteoglycans, and glycoproteins.
Extracellular Matrix (ECM)
The organized meshwork of macromolecules surrounding and underlying cells.
Fibers
Structural components of the ECM that vary in composition.
Composition of ECM
Varies in composition, containing ground substance, multiadhesive glycoproteins, and fibers.
Extracellular Environment
Includes the ECM, water, and other small molecules, constituting the environment outside the cells.
Metabolic Activities
The activities of cells that can be affected by the ECM.
Cell-ECM Interactions
The influence of the ECM on the shape, migration, and interactions of cells.
Cell Differentiation
The process influenced by the ECM, leading to cells taking on specialized functions.
Physical Support
Provided by the ECM against compressive and tensile forces.
ECM Function
Affects cell metabolism, shape, migration, interactions, division, and differentiation, while also providing physical support.
What is the watery largely unstained extracellular material rich in hydrated glycosaminoglycans?
Ground substance (the extracellular matrix, ECM)
What are Glycosaminoglycans (GAGs)?
They are a family of unbranched polysaccharide chains of repeating disaccharide units with multiple negative charges that constitute a large volume fraction of the ECM.
What is the structure of Glycosaminoglycans (GAGs)?
They are a polymer of repeating disaccharide units.
What is the function of Glycosaminoglycans (GAGs)?
They bind H2O in connective tissue due to their negative charges and act as a cushion, allowing tissue to temporarily adapt its shape under externally applied stress and then return to its original state.
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A flashcard deck covering cell biology topics from 2 weeks ago, including ECM, collagen, and cell junctions.
Biology
Anatomy
Cell Biology
Extracellular Matrix
Collagen
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