/
Core Immunology Concepts
Save to my account
Sign up
Core Immunology Concepts
Core Immunology Concepts
Study
1
Question
What are mitogens in immunology?
Answer
Toxins that non-specifically stimulate lymphocytes
2
Question
What type of immunity is fabotherapy an example of?
Answer
Artificial passive immunity
3
Question
Which protein participates in all three complement activation pathways?
Answer
C3
4
Question
Which complement molecule acts as an opsonin?
Answer
C3b and C4b
5
Question
Which complement components cause inflammation as anaphylatoxins?
Answer
C3a and C5a
6
Question
Which Fc receptor mediates placental transfer of IgG?
Answer
FcRn
7
Question
Which antibody isotype is most abundant in plasma?
Answer
IgG
8
Question
What type of interactions characterize antigen-antibody reactions?
Answer
Non-covalent and reversible
9
Question
What preformed mediator do mast cells release during inflammation?
Answer
Histamine
10
Question
What type of epitopes do B lymphocytes recognize?
Answer
Conformational epitopes
11
Question
What do virus-infected cells primarily produce?
Answer
Type I interferons
12
Question
What molecule specifically binds an antibody or interacts with TCR?
Answer
Antigen
13
Question
Which complement receptor eliminates immune complexes?
Answer
CR1
14
Question
What membrane regulator inhibits complement-mediated cell lysis?
Answer
MACIF (CD59)
15
Question
What gene segments encode light chains of antibodies?
Answer
VJ and C
16
Question
What molecule aids non-oxidative phagocytosis?
Answer
Lysozyme
17
Question
Which cells recognize linear epitopes?
Answer
T lymphocytes
18
Question
What is the biological function of antibodies induced by tetanus toxoid?
Answer
Neutralization
19
Question
What innate immunity peptide has microbicidal activity from skin and epithelia?
Answer
Defensins
20
Question
Which intracellular receptors recognize viral PAMPs?
Answer
TLR3 and RIG-I
21
Question
Which cell constitutively expresses low-affinity IgE receptor?
Answer
Eosinophil
22
Question
What tissues does TNF-α primarily act on for systemic effects?
Answer
Liver and endothelium
23
Question
Which antibody isotype dominates secondary humoral response?
Answer
IgG
24
Question
Which cell constitutively expresses the predominant antibody isotype receptor?
Answer
Neutrophil (FcγR)
25
Question
Which Fc receptor on NK cells mediates ADCC?
Answer
FcγRIII
26
Question
What type of receptors are PCR and MBL?
Answer
Soluble
27
Question
Which gene segment is absent in light chains of antibodies?
Answer
D
28
Question
Which endosomal receptors on macrophages recognize viral structures?
Answer
TLR3 and TLR7
29
Question
What is the effector function of CD4 T cells?
Answer
Secretion of cytokines
30
Question
Which intracellular receptor recognizes muramyl-dipeptide in bacterial cell walls?
Answer
NOD2